Humoral immune response for early diagnosis of breast carcinoma

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Abstract
Mortality from cancer, in particular breast carcinomas, has decreased in the last decade, due principally to early diagnosis of the disease. A major effort to improve diagnosis further by identifying serological markers indicative of early-stage disease has met with little success, except for a few oncotypes not including breast carcinoma. Indeed, the release of tumor markers into the serum is a late event associated with a large tumor mass and thus not useful for early diagnosis [1].

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