The Relation of Serum Stability to the Development of Arteriosclerosis

Abstract
The rate of turbidity formation caused by theadditionofappropriateamts.of Mn2+, Ni2+, Cu2+, or Zn2+ ions to undiluted serums, under standardized conditions, was taken as a measure of the colloid stability of serum. The serums of 133 patients with indications of arteriosclerosis, by the above criteria had less colloid stability than the serums of 60 normal controls in about 90% of the cases. It is suggested that the interaction of the arterial walls of the arteries with blood of low serum stability may gradually lead to a decreased colloid stability of the arteries and to arteriosclerosis.

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