Biosynthesis of the Cinchona alkaloids: late stages of the pathway

Abstract
A combination of evidence from isolations and from tracer experiments supports the sequence (1)→(7) and (9)(11) and (13)(and similarly for the methoxylated series) as the pathway to the Cinchona alkaloids: the results also point to cinchonaminal (3) as being the key intermediate between (1) and (7).

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