Studies of Cd, Zn and Cu levels in human kidney tumours and normal kidney
- 1 March 1986
- journal article
- research article
- Published by Springer Nature in Urological Research
- Vol. 14 (2) , 105-108
- https://doi.org/10.1007/bf00257895
Abstract
Summary The distribution of Cd, Zn and Cu was analyzed in nuclear, mitochondrial and cytosol cellular fractions of renal tumours and normal surrounding kidney tissues by electrothermal atomic absorption spectrometry (AAS). The normal kidney tissues were separated into cortical and medullary parts. A significant decrease of the Cd-levels was found in all cellular fractions from normal kidney to tumour tissues (hypernephroma). The Zn values varied strongly. We noted a slight decrease of Zn levels in renal tumour. The Cu concentration in the nucleus of kidney tumours was significantly increased.Keywords
This publication has 9 references indexed in Scilit:
- Determination of the distribution of Zinc and Cadmium in cellular fractions of BPH, normal prostate and prostatic cancers of different histologies by atomic and laser absorption spectrometry in tissue slicesUrological Research, 1984
- Histochemical changes in protein disulphide bonds in rat liver and kidney after chronic cadmium administration, and the possible relation to metallothioneinArchives of Toxicology, 1984
- ZINC AND CADMIUM IN CELL-FRACTIONS OF PROSTATIC-CANCER TISSUES OF DIFFERENT HISTOLOGICAL GRADING IN COMPARISON TO BPH AND NORMAL PROSTATE1984
- Copper and Zinc levels in normal and malignant tissuesCancer, 1983
- Renal cadmium content in the West of ScotlandUrological Research, 1983
- Zinc and cadmium concentration in prostatic carcinoma of different histological grading in comparison to normal prostate tissue and adenofibromyomatosis (BPH)Urological Research, 1982
- Role of cadmium in carcinogenesis with special reference to cancer of the prostateEnvironmental Health Perspectives, 1981
- Association of cadmium with renal cancerCancer, 1976
- Mechanism for cadmium and zinc antagonism of copper metabolismBiochemical and Biophysical Research Communications, 1970