Effect of ischaemia and infarction on the metabolism and function of the isolated, perfused rat heart

1 May 1972

journal article
research article
Published by Oxford University Press (OUP) in Cardiovascular Research

Vol. 6 (3) , 284-294
https://doi.org/10.1093/cvr/6.3.284

Abstract

The long-term effects of left coronary artery occlusion were studied on the metabolism and function of the isolated, perfused rat heart. Metabolic studies indicated anaerobiosis following occlusion, accompanied by a depression in ATP and CrP contents. Myocardial function was significantly depressed within 30 min, but returned to normal after one month.

Keywords

CORONARY ARTERY
MYOCARDIAL FUNCTION
ARTERY OCCLUSION
METABOLIC STUDIES
TERM EFFECTS
SIGNIFICANTLY DEPRESSED
CRP CONTENTS
INDICATED ANAEROBIOSIS

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