Alterations in Serum Enzymes in Chronic Renal Failure
- 28 September 1970
- journal article
- research article
- Published by American Medical Association (AMA) in JAMA
- Vol. 213 (13) , 2263-2265
- https://doi.org/10.1001/jama.1970.03170390053014
Abstract
Serum lactic dehydrogenase (LDH), glutamic oxaloacetic transaminase (GOT), and amylase levels were determined in 76 chronically uremic patients. Serum LDH was increased in 77% of 486 determinations, and only 10% of the abnormal levels could be accounted for by pathological conditions known to increase LDH. Serum GOT levels were generally normal. Serum amylase was increased in 32% of 175 determinations. There is a high incidence of abnormal LDH and amylase levels in uremic patients. We caution against overinterpretation of these findings and the costly and often unnecessary search for their significance.Keywords
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