DEFECTIVE MICROBICIDAL FUNCTION OF NEUTROPHILS IN HEMATOLOGICAL MALIGNANCIES AND LYMPHOMAS - CORRECTION BY LEVAMISOLE INVITRO

  • 1 January 1978
    • journal article
    • research article
    • Vol. 29  (5) , 159-161
Abstract
The ability of neutrophils to kill Candida guilliermondii was investigated in patients with various hematological malignancies and lymphomas. Of 24 patients, 12 showed significant depression of Candida killing in vitro in comparison with normal controls. The addition of levamisole to the test system, in a concentration of 1 .times. 10-7 M, resulted in the correction of the Candida killing defect in 7 of 8 patients.