Studies on chemical induction of chromosomal aberrations in postcopulation germ cells and zygotes of female mice. II. Induction of heritable translocations.
- 1 January 1983
- journal article
- research article
- Published by Genetics Society of Japan in The Japanese Journal of Genetics
- Vol. 58 (4) , 353-359
- https://doi.org/10.1266/jjg.58.353
Abstract
The induction of heritable translocations with chemicals in postcopulation germ cells of female mice was investigated. In the methyl methanesulfonate (MMS)-treated group (100mg/kg), 14 partially sterile and 5 sterile males out of 118 F1 male progeny were found. In contrast, in the mitomycin C (MC)- treated group (3mg/kg and 4mg/kg) the frequencies were low. These results indicate that the yield of heritable translocations parallels the formation of chromosome-type aberrations at the first cleavage reported previously.This publication has 4 references indexed in Scilit:
- Chromosome aberrations induced by mitomycin c treatment in early spermatids of male mice.The Japanese Journal of Genetics, 1981
- Studies on chemical induction of chromosomal aberrations in postcopulation germ cells and zygotes of female mice. I. Comparative studies on the frequency of first-cleavage chromosomal aberrations and dominant-lethal mutations.The Japanese Journal of Genetics, 1981
- Formation of chromosome-type aberrations at the first cleavage after MMS treatment in late spermatids of miceCytogenetic and Genome Research, 1981
- RELATIONSHIP BETWEEN CHROMOSOME ABERRATIONS IN THE FIRST-CLEAVAGE METAPHASES AND UNSCHEDULED DNA SYNTHESIS FOLLOWING PATERNAL MMS TREATMENTThe Japanese Journal of Genetics, 1980