Splicing of a rare class of introns by the U12-dependent spliceosome
- 1 January 2005
- journal article
- review article
- Published by Walter de Gruyter GmbH in Biological Chemistry
- Vol. 386 (8) , 713-24
- https://doi.org/10.1515/bc.2005.084
Abstract
Pre-mRNA splicing is catalyzed by two unique spliceosomes, designated U2- or U12-dependent. In contrast to the well-characterized U2-dependent spliceosome, much remains to be learned about the less abundant U12-type spliceosome. This review focuses on recent advances in elucidating the structure and function of the minor U12-dependent spliceosome. Interesting similarities and differences between the U12- and U2-dependent spliceosomes are also highlighted.Keywords
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