Immunology of HIV Infection, I: Biology of the Interferons
- 1 October 1990
- journal article
- research article
- Published by Mary Ann Liebert Inc in AIDS Research and Human Retroviruses
- Vol. 6 (10) , 1149-1156
- https://doi.org/10.1089/aid.1990.6.1149
Abstract
Interferons (IFN) are the prototypic biologic response modifiers. They comprise a multigene family of regulatory proteins and glycoproteins that affect a variety of cellular functions, including normal and neoplastic cell growth, immune reactivity, and host-parasite interactions. Their importance to basic cell biology and cellular immune defense, and their interactions with human immunodeficiency viruses (HIV) on the molecular and cellular levels, form the basis for this review.This publication has 35 references indexed in Scilit:
- The role of interferons in the control of HIV replication in macrophagesClinical Immunology and Immunopathology, 1990
- The interferon-induced Mx-homologous protein in people with symptomatic HIV-1 infectionAIDS, 1990
- A phase I trial of recombinant human interferon-γ in patients with Kaposi's sarcoma and the acquired immunodeficiency syndrome (AIDS)Journal of Clinical Immunology, 1989
- Downregulation of interferon alpha but not gamma receptor expression in vivo in the acquired immunodeficiency syndrome.Journal of Clinical Investigation, 1988
- PolyI.polyC12U-mediated inhibition of loss of alloantigen responsiveness viral replication in human CD4+ T cell clones exposed to human immunodeficiency virus in vitro.Journal of Clinical Investigation, 1987
- INTERFERONS AND THEIR ACTIONSAnnual Review of Biochemistry, 1987
- Decreased expression of human class II antigens on monocytes from patients with acquired immune deficiency syndrome. Increased expression with interferon-gamma.Journal of Clinical Investigation, 1984
- Identification of two distinct regulatory regions adjacent to the human β-interferon geneCell, 1983
- Acid-Labile Human Leukocyte Interferon in Homosexual Men with Kaposi's Sarcoma and LymphadenopathyThe Journal of Infectious Diseases, 1982
- Effect of Interferon on Murine Leukaemia Virus Infection. IV. Formation of Non-infectious Virus in Chronically Infected CellsJournal of General Virology, 1979