The Toxic Effects of Alcohol on Folate Metabolism

Publisher Website
Google Scholar
Abstract
Alcohol exerts toxic effects on folate homeostasis through impaired intake, because of dietary deprivation or malabsorption. It also has a direct effect on internal folate metabolism which involves reversible tissue sequestration, increased polyglutamate synthesis, decreased biliary folate and a resulting reduction in serum folate levels and tissue supply. Alcoholism is associated with a number of changes in cellular metabolism which can lead to organ damage.

This publication has 18 references indexed in Scilit: