The Microbial Flora of Saliva and Faeces in Individuals with Selective IgA Deficiency and Common Variable Immunodeficiency

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Abstract
The microflora was determined in saliva and faecal samples from 36 individuals with selective TgA deficiency and 28 individuals with common variable immunodeficiency. Most microbial species in both saliva and faeces in individuals with selective IgA deficiency and common variable immunodeficiency remained unchanged compared to healthy normal individuals. In saliva statistically significant increased numbers of Actinomyces species and decreased numbers of Staphylococcus epidermidis were noted compared to healthy normal individuals. In faeces, the anaerobic microorganisms in individuals with selective IgA deficiency and in γ-globulin-treated patients with common variable immunodeficiency were increased compared to healthy normal individuals. Elevated numbers of enterococci were seen in individuals with selective IgA deficiency and in untreated individuals with common variable immunodeficiency. Both individuals with selective IgA deficiency and γ-globulin-treated patients with common variable immunodeficiency showed increased numbers of Clostridia.