A New Synthesis of α-Santalol
- 1 November 1976
- journal article
- Published by Oxford University Press (OUP) in Bulletin of the Chemical Society of Japan
- Vol. 49 (11) , 3351-3352
- https://doi.org/10.1246/bcsj.49.3351
Abstract
A new synthesis of α-santalol (1) is described. 1-Benzyloxy-4-bromo-2-methyl-2-butene (6) was converted by the reaction with nickel carbonyl to the π-allylic nickel bromide complex (7), which reacted with (−)-π-bromotricyclene (8) to afford benzyl ether (2). The benzyl ether (2) was led to (1) (cis: trans=40: 60) by reductive cleavage of the benzyloxy group.Keywords
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