Hyperemia, CO2 responsiveness, and autoregulation in the white matter following experimental spinal cord injury

Publisher Website
Google Scholar
Abstract
The results are presented of a controlled, randomized study of alterations in spinal cord blood flow, CO2 responsiveness and autoregulation following experimental spinal cord injury in cats. Permanent paraplegia is associated with persistent hyperemia, loss of CO2 responsiveness and impaired autoregulation in the white matter at the injury site. Probable mechanisms underlying these changes in spinal cord vasomotor control are discussed. Marked similarities between vascular responses of injured spinal cord and luxury perfusion of the brain are pointed out.