The Effect of Inhibitors of DNA Repair on the Genetic Instability of Streptomyces cattleya
- 1 April 1984
- journal article
- research article
- Published by Microbiology Society in Microbiology
- Vol. 130 (4) , 887-892
- https://doi.org/10.1099/00221287-130-4-887
Abstract
Using spores of S. cattleya NRRL 8057 and the virulent actinophage VC11, it was shown that a caffeine-inhibitable, host-mediated UV repair system is active in spores during early development. Evidence was also found for the presence of an arsenite, inhibitable UV repair system. The caffeine-inhibitable UV repair system was involved in the induction of genetic instability in S. cattleya. The arsenite system may be implicated in the repair of such events. Genetic instability was also induced by single strand breaks in DNA caused by 32P.Keywords
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