A technique for anodally blocking large nerve fibres through chronically implanted electrodes.
Open Access
- 1 December 1980
- journal article
- research article
- Published by BMJ in Journal of Neurology, Neurosurgery & Psychiatry
- Vol. 43 (12) , 1083-1090
- https://doi.org/10.1136/jnnp.43.12.1083
Abstract
If a spinal root of a baboon or rhesus monkey is trapped in an initially loose-fitting silicone rubber channel containing two or more platinum electrodes, electrical pulses sent through these electrodes can stimulate nerve fibres close to the cathode and block the resulting impulses close to the anode. We show (1) how anodal break excitation and excitation of fibres outside the silicone rubber channel can be avoided; (2) that an implant 26 months old behaves like a recent one; (3) that in a root containing somatic motor fibres and parasympathetic fibres, all somatic motor fibres can be blocked and most or all parasympathetic fibres excited but not blocked; (4) that provided that the electrodes pass no net direct current, prolonged stimulation with block can be harmless; (5) how block can be achieved in one direction only along a root; (6) that a peripheral nerve can be blocked by the same techniques.Keywords
This publication has 13 references indexed in Scilit:
- Generation of Unidirectionally Propagated Action Potentials in a Peripheral Nerve by Brief StimuliScience, 1979
- Selective Activation of peripheral nerve fibre groups of different diameter by triangular shaped stimulus pulses.The Journal of Physiology, 1977
- An implant to empty the bladder or close the urethra.Journal of Neurology, Neurosurgery & Psychiatry, 1977
- Urodynamic Observations Following Spinal TraumaBritish Journal of Urology, 1975
- The electrical properties of the slow muscle fibre membraneThe Journal of Physiology, 1956
- Cholinergic and inhibitory synapses in a pathway from motor‐axon collaterals to motoneuronesThe Journal of Physiology, 1954
- Small‐nerve junctional potentials. The distribution of small motor nerves to frog skeletal muscle, and the membrane characteristics of the fibres they innervate*The Journal of Physiology, 1953
- A theory of the effects of fibre size in medullated nerveThe Journal of Physiology, 1951
- The site of excitation in the nerve trunk of the frogThe Journal of Physiology, 1949
- Temperature and ExcitabilityThe Journal of Physiology, 1896