Spontaneous and nerve-evoked quantal transmission in regenerated motor terminals

Abstract
Quantal acetylcholine release was studied in sciatic nerve — extensor digitorum longus muscle preparations from normal rats and in reinnervated muscles at different times following peroneus nerve crush. The efficiency of nerve-evoked transmission was regained almost completely at a time (20 days after crush) when the secretory response to increased extracellular K + was very weak. This suggests that K + -induced secretion might be activated through mechanisms at least partially different from those involved in the response to nerve stimulation.

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