The finding of [human] multiple respiratory or skin allergies together with a high rate of improvement by desensitization shows that allergy is apparently predisposing factor for the chronicity or recurrence of vaginal or dermatologic moniliasis. Desensitization with Candida albicans antigen was the mainstay in the treatment of resistant dermatologic or vaginal moniliasis, and the sole form of therapy in cases of nail involvement with deep seated lesions out of the reach of topical agents.