Acute myopathy and neuropathy in status asthmaticus: Case report and literature review

Abstract
A 38‐year‐old woman developed acute, severe weakness during the treatment of status asthmaticus that included high‐dose intravenous corticosteroids. A muscle biopsy and EMG indicated a myopathy, and nerve conduction studies disclosed a neuropathic component. In association with corticosteroid tapering, the clinical, EMG, and nerve conduction abnormalities resolved. In some patients, intensive treatment of status asthmaticus may cause a reversible, toxic disorder of muscle and nerve. © 1993 John Wiley & Sons, Inc.