BILE-DUCT DYSKINESIA - CLINICAL AND MANOMETRIC STUDY

  • 1 January 1984
    • journal article
    • research article
    • Vol. 87  (4) , 759-762
Abstract
Unexplained right upper quadrant symptoms have often been attributed to bile duct dyskinesia. The pressure profile of the sphincter of Oddi was evaluated in 10 patients with recurrent episodes of right upper quadrant pain, intermittent mild transaminasemia and a normal pancreatobiliary tract. Nine healthy volunteers served as control. A triple-lumen catheter with an external diameter of 1.7 mm and recording sites at 2-mm intervals was introduced into the papilla through the endoscope. Ductal pressure, basal sphincter of Oddi pressure, and the amplitude and propagation direction of the phasic contractions of the sphincter were determined in patients and subjects. All measurements were performed relative to duodenal pressure, which was taken as zero. There was no significant difference between patients and subjects in the amplitude and frequency of phasic contractions of sphincter of Oddi. In contrast, the patients demonstrated a higher sphincter of Oddi pressure (P < 0.005) and increased proportion of retrograde propagation direction of phasic contractions (P < 0.01). A subpopulation of patients with unexplained abdominal pain evidently demonstrated abnormal pressure profile of the sphincter of Oddi.

This publication has 0 references indexed in Scilit: