PAMP and PARL, two novel putative metalloproteases interacting with the COOH-terminus of Presenilin-1 and -2
- 14 May 2001
- journal article
- Published by SAGE Publications in Journal of Alzheimer's Disease
- Vol. 3 (2) , 181-190
- https://doi.org/10.3233/jad-2001-3203
Abstract
The familial Alzheimer's disease gene products, presenilin-1 and presenilin-2 (PS1 and PS2), are involved in amyloid β-protein precursor processing (AβPP), Notch receptor signaling, and programmed cell death. However, the molecular mechanisms by whicKeywords
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