The design of potent and stable benzisothiazolone inhibitors of human leukocyte elastase
- 1 February 1995
- journal article
- Published by Elsevier in Bioorganic & Medicinal Chemistry Letters
- Vol. 5 (4) , 331-336
- https://doi.org/10.1016/0960-894x(95)00030-w
Abstract
No abstract availableKeywords
This publication has 15 references indexed in Scilit:
- A benzisothiazolone class of potent, selective mechanism-based inhibitors of human leukocyte elastaseBioorganic & Medicinal Chemistry Letters, 1994
- Design of Orally Active, Non-Peptidic Inhibitors of Human Leukocyte ElastaseJournal of Medicinal Chemistry, 1994
- Synthetic Inhibitors of ElastaseMedicinal Research Reviews, 1994
- Chapter 20. Human Leukocyte Elastase InhibitorsPublished by Elsevier ,1994
- Orally active .beta.-lactam inhibitors of human leukocyte elastase-1. Activity of 3,3-diethyl-2-azetidinonesJournal of Medicinal Chemistry, 1992
- The effect of N-acyl substituents on the stability of monocyclic β-lactam inhibitors of human leukocyte elastaseBioorganic & Medicinal Chemistry Letters, 1992
- Design and synthesis of 4H-3,1-benzoxazin-4-ones as potent alternate substrate inhibitors of human leukocyte elastaseJournal of Medicinal Chemistry, 1990
- Serum enzymes of drug metabolismPharmacology & Therapeutics, 1987
- Antielastases of the human alveolar structures. Implications for the protease-antiprotease theory of emphysema.Journal of Clinical Investigation, 1981
- Elastolytic Activity in Pulmonary Lavage Fluid from Patients with Adult Respiratory-Distress SyndromeNew England Journal of Medicine, 1981