Growth hormone enhances basement membrane thickening in experimental diabetes
- 1 December 1978
- journal article
- research article
- Published by Springer Nature in Diabetologia
- Vol. 15 (6) , 487-489
- https://doi.org/10.1007/bf02342875
Abstract
Injection of porcine growth hormone (200 μg) or saline 5 days a week for 16 to 20 weeks in streptozotocin-diabetic rats showed that compared to saline growth hormone produced a 2 1/2-fold larger increase in glomerular capillary basement membrane thickness (2p=0.027). The possible significance of this effect of an elevated level of growth hormone for diabetic microangiopathy is discussed.This publication has 7 references indexed in Scilit:
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- DIABETES, DIABETIC ANGIOPATHY, AND GROWTH HORMONEThe Lancet, 1970