GLOMERULOTROPIC ACTIVITY OF AN ACETONE EXTRACT OF PINEAL TISSUE1
- 1 August 1959
- journal article
- research article
- Published by The Endocrine Society in Endocrinology
- Vol. 65 (2) , 239-241
- https://doi.org/10.1210/endo-65-2-239
Abstract
A crude acetone-soluble fraction of beef pineal tissue was assayed for steroidogenic activity in the decere-brate dog. Aldosterone secretion was markedly stimulated without a significant effect on cortisol output. When the material was partitioned between water and hexane, the hexane fraction was found to contain the activity. The finding is taken as additional evidence for the existence of glomerulotropin, a specific hormone for aldosterone secretion, in pineal tissue or an adjacent structure.Keywords
This publication has 2 references indexed in Scilit:
- Regulation of Aldosterone SecretionPhysiological Reviews, 1958
- Isolation and Identification of Aldosterone from Adrenal Venous BloodExperimental Biology and Medicine, 1954