Isolation and biomimetic conversion of 4,21-dehydrogeissoschizine

Abstract
4,21-Dehydrogeissochizine hydrochloride (4), a postulated intermediate in the biosynthesis of heteroyohimbine alkaloids, has been isolated from a plant source; it has been converted into cathenamine (5) and isovallesiachotamine (3), in addition to heteroyohimbine and geissoschizine-type alkaloids, (9), (11) and (6), (7), respectively.

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