A retrospective study of follicular lymphomas

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Abstract
Sixty-four cases of follicular lymphoma followed-up for 10 years bave been studied. The influence of age, sex, histologic appearance, immunophenotype and T-cell content on prognosis has been examined. Initial evaluation indicated that increasing age, relatively low numbers of intrafollicular T-cells and absence of mantle zones around the neoplastic follicles were associated significantly with mortality. Multiple regression analysis with adjustment for age and sex was performed and the only significant variable was then found to be the histological grade.