Mapping of Functional Neural Pathways by Autoradiographic Survey of Local Metabolic Rate with [ 14 C]Deoxyglucose
- 7 March 1975
- journal article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 187 (4179) , 850-853
- https://doi.org/10.1126/science.1114332
Abstract
An enzymatic preparation from human brain converts tryptamine to tryptoline (9H-1,2,3,4-tetrahydropyrido(3,4-b)indole) in the presence of 5-methyltetrahydrofolic acid. Similarly, N-methyltryptamine and 5-hydroxytryptamine yield 1-methyltryptoline and 5-hydroxytryptoline, respectively. Neither in vitro nor in vivo formation of these compounds by human tissues has been described.Keywords
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