Sirtuin 1 Reduction Parallels the Accumulation of Tau in Alzheimer Disease
Open Access
- 1 January 2009
- journal article
- research article
- Published by Oxford University Press (OUP) in Journal of Neuropathology and Experimental Neurology
- Vol. 68 (1) , 48-58
- https://doi.org/10.1097/nen.0b013e3181922348
Abstract
Aging and metabolism-related disorders are risk factors for Alzheimer disease (AD). Because sirtuins may increase the life span through regulation ofKeywords
This publication has 67 references indexed in Scilit:
- Paths of Convergence: Sirtuins in Aging and NeurodegenerationPublished by Elsevier ,2008
- SIRT1 transgenic mice show phenotypes resembling calorie restrictionAging Cell, 2007
- SIRT1 deacetylase protects against neurodegeneration in models for Alzheimer's disease and amyotrophic lateral sclerosisThe EMBO Journal, 2007
- A Century of Alzheimer's DiseaseScience, 2006
- Resveratrol improves health and survival of mice on a high-calorie dietNature, 2006
- Sirtuins deacetylate and activate mammalian acetyl-CoA synthetasesProceedings of the National Academy of Sciences, 2006
- Global prevalence of dementia: a Delphi consensus studyPublished by Elsevier ,2006
- Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-γNature, 2004
- Characterization of Five Human cDNAs with Homology to the Yeast SIR2 Gene: Sir2-like Proteins (Sirtuins) Metabolize NAD and May Have Protein ADP-Ribosyltransferase ActivityBiochemical and Biophysical Research Communications, 1999
- Peroxisomal retroconversion of docosahexaenoic acid (22:6(n−3)) to eicosapentaenoic acid (20:5(n−3)) studied in isolated rat liver cellsBiochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1991