Characteristics of thymus-homing bone marrow cells.
Open Access
- 1 July 1983
- journal article
- research article
- Published by Oxford University Press (OUP) in The Journal of Immunology
- Vol. 131 (1) , 64-69
- https://doi.org/10.4049/jimmunol.131.1.64
Abstract
Using a short-term in vivo assay, we studied bone marrow cells capable of homing to the thymus of lethally irradiated recipients. In the bone marrow, these cells lack the T cell markers Thy-1 and Lyt. Soon after their homing into the thymus, however, the immigrants begin to express Thy-1 and Lyt antigens, but not TL antigen. Unexpectedly, Lyt antigens appear to be expressed before Thy-1. These thymus-homing bone marrow cells seem to be already separated from the B cell lineage. Most of the homing cells are engaged in the cell cycle.This publication has 1 reference indexed in Scilit:
- Expression of Thymocyte Surface Alloantigens in the Fetal Mouse Thymus in vivo and in Organ CultureThe Journal of Immunology, 1977