Ring Selective Lithiation of 3,5-Lutidine. A New Route to Heterocyclic Building Blocks.
- 1 March 2002
- journal article
- letter
- Published by Georg Thieme Verlag KG in Synlett
- Vol. 2002 (04) , 0628-0630
- https://doi.org/10.1055/s-2002-22702
Abstract
The first direct ring lithiation of 3,5-lutidine has been performed by the BuLi-LiDMAE reagent. Successful sequential metallations and electrophilic condensations have been performed giving access to new useful polysubstituted pyridines.Keywords
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