Altered levels of microtubule proteins in brains of Alzheimer's disease patients
- 1 January 1989
- journal article
- research article
- Published by Springer Nature in Acta Neuropathologica
- Vol. 78 (1) , 47-51
- https://doi.org/10.1007/bf00687401
Abstract
The amount of microtubule protein present in the total soluble protein from brains of Alzheimer's disease patients and from brains of non-Alzheimer age-matched controls, were determined by radioimmunoassay. No differences were found in the amount of tubulin or microtubule-associated protein MAP2 present in either group. However, the amount of tau protein or MAP1 from the brains of Alzheimer's disease patients was about half of that present in their control counterparts.Keywords
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