Hypoglycemic Activity ofSalvia lavandulifolia

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Abstract
The hypoglycemic activity of infusions and suspensions of Salvia lavandulifolia was studied in normoglycemic, hypoglycemic, and alloxan-diabetic rabbits. Variations in circulating levels of insulin were also studied in normoglycemic animals. The greatest decreases in glucose levels (17-18%) were obtained with doses > 0.250 mg/kg in normoglycemic rabbits. No effect was seen on insulin levels. In glucose-induced hyperglycemia, antidiabetic activity was seen only when the Salvia infusion was administered simultaneously with glucose. In alloxan-diabetic rabbits, the daily administration of 0.250 mg/kg of infusion resulted in a 33% decrease in blood glucose levels.

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