Effect of Dimethyl Sulfoxide and Glycerol on Cation Content of Freeze-Thawed Cardiac Muscle
- 1 August 1962
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 110 (4) , 789-791
- https://doi.org/10.3181/00379727-110-27651
Abstract
The effects of dimethyl sulfoxide (DMS) and glycerol on K and Na content of freeze-thawed isolated rabbit heart muscle were determined. Both right atrial and left ventricular tissue lost K and gained Na after freeze-thawing compared to freshly dissected tissue. The presence of 10% DMS or 15% glycerol during freeze-thawing did not prevent this loss of K or gain of Na. Glycerol also produced a loss of tissue K even in the absence of freeze- thawing.Keywords
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