In Vitro Susceptibilities of Chlamydia pneumoniae Isolates from German Patients and Synergistic Activity of Antibiotic Combinations
- 1 July 1999
- journal article
- research article
- Published by American Society for Microbiology in Antimicrobial Agents and Chemotherapy
- Vol. 43 (7) , 1808-1810
- https://doi.org/10.1128/aac.43.7.1808
Abstract
The susceptibilities of six Chlamydia pneumoniae type strains and of six German patient isolates to erythromycin, azithromycin, roxithromycin, clarithromycin, doxycycline, ofloxacin, and rifampin were investigated. MICs and minimal chlamydicidal concentrations were all within the ranges reported previously. Combinations of azithromycin with either ofloxacin, doxycycline, or rifampin, as well as combinations of three antibiotics (rifampin, azithromycin, and ofloxacin or doxycycline), showed synergistic activity against C. pneumoniae .Keywords
This publication has 21 references indexed in Scilit:
- Susceptibility of Chlamydia pneumoniae to Azithromycin and Doxycycline: Methodological Aspects on the Determination of Minimal Inhibitory and Minimal Bactericidal ConcentrationsScandinavian Journal of Infectious Diseases, 1997
- Mycoplasma pneumoniae and Chlamydia pneumoniae in pediatric community-acquired pneumoniaThe Pediatric Infectious Disease Journal, 1995
- Effects of two antibiotic regimens on course and persistence of experimental Chlamydia pneumoniae TWAR pneumonitisAntimicrobial Agents and Chemotherapy, 1995
- Susceptibility of Chlamydia pneumoniae to oral agents commonly used in the treatment of respiratory infectionJournal of Antimicrobial Chemotherapy, 1994
- In vitro and in vivo activities of azithromycin, a new azalide antibiotic, against chlamydiaAntimicrobial Agents and Chemotherapy, 1994
- Antimicrobial susceptibility and therapy of infections caused by Chlamydia pneumoniaeAntimicrobial Agents and Chemotherapy, 1994
- In vitro activity of azithromycin (CP-62,993) against Chlamydia trachomatis and Chlamydia pneumoniaeAntimicrobial Agents and Chemotherapy, 1993
- The in-vitro activity of clarithromycin and other macrolides against the type strain of Chlamydia pneumoniae (TWAR)Journal of Antimicrobial Chemotherapy, 1991
- SEROLOGICAL EVIDENCE OF AN ASSOCIATION OF A NOVEL CHLAMYDIA, TWAR, WITH CHRONIC CORONARY HEART DISEASE AND ACUTE MYOCARDIAL INFARCTIONThe Lancet, 1988
- In Vitro Activity of Rifamycins Alone and in Combination with Other Antibiotics Against Chlamydia trachomatisClinical Infectious Diseases, 1983