Polyamines Stimulate Suppression of Amber Termination Codons in vitro by Normal tRNAs
- 1 April 1980
- journal article
- research article
- Published by Wiley in European Journal of Biochemistry
- Vol. 105 (3) , 445-451
- https://doi.org/10.1111/j.1432-1033.1980.tb04519.x
Abstract
Polyamines, such as spermine and spermidine, are able to stimulate reading of amber termination codons on viral messenger RNAs in vitro. This phenomenon is not due to an overall increase of error frequency during translation, but to a specific effect on a normal tRNA that is present in various eukaryotic cell preparations. The enhancement of reading of termination codons by normal tRNAs should be of major importance for the expression of specific genes in eukaryotic cells.This publication has 40 references indexed in Scilit:
- Fidelity of protein synthesis in vitro is increased in the presence of spermidineFEBS Letters, 1979
- Synthesis and accumulation of polyamines and S-adenosylmethionine in Chinese cabbage infected by turnip yellow mosaic virusBiochemical and Biophysical Research Communications, 1979
- Differential translation of turnip yellow mosaic virus mRNAs in vitroBiochemical and Biophysical Research Communications, 1978
- Aminoglycoside antibiotics and eukaryotic protein synthesis: stimulation of errors in the translation of natural messengers in extracts of cultured human cellsBiochemistry, 1978
- Aminoglycoside antibiotics and eukaryotic protein synthesis: structure-function relationships in the stimulation of misreading with a wheat embryo systemBiochemistry, 1978
- Translation of TYMV RNA into high molecular weight proteinsFEBS Letters, 1978
- Responsibility of 16S RNA for the stimulation of polypeptide synthesis by spermidineBiochemical and Biophysical Research Communications, 1977
- Translation of natural mRNA in cell-free systems from a polyamine-requiring mutant of Escherichia coliBiochemical and Biophysical Research Communications, 1977
- Binding of transfer rna to polyamines in preference to Mg2+Biochemical and Biophysical Research Communications, 1975
- Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4Nature, 1970