Plasma Levels and Urinary Excretion of Injected Myanesin in Dogs.
- 1 October 1947
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 66 (1) , 256-260
- https://doi.org/10.3181/00379727-66-16056
Abstract
A colorimetric method was devised for detn. of myanesin in plasma and in urine. The rapid decay of free myanesin in dog plasma explains the brevity of its pharmgeologic action. In the dog, from 0.1-2.0% of the administered dose is excreted as free myanesin; from 32-42% of the administered dose is excreted as conjugated myanesin in 24 hrs., possibly as the glucuronide.Keywords
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