Pyrrole and Pyrazole Ring Closure in Heterogeneous Media
- 1 January 1986
- journal article
- research article
- Published by Georg Thieme Verlag KG in Synthesis
- Vol. 1986 (05) , 409-411
- https://doi.org/10.1055/s-1986-31655
Abstract
Pyrroles and pyrazoles may be conveniently prepared by dispersing primary amines or hydrazines and 1,4- or 1,3-diketones, respectively, on alumina or clay (montmorillonite K 10) without solvent, keeping the mixture at 20°C or higher temperatures for 1-26 h, and then eluting the product with dichloromethane.Keywords
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