Joint Disease in Mice "Thyroidectomized" with Radio-iodine I131.

Abstract
In DBA mice thyroidectomized with I131, a joint disease was observed which differs from osteoarthritic changes occurring spontaneously in old mice. Males were more susceptible than females. In males there was a strong positive correlation between the incidence of hypophyseal tumors induced by the isotope and the incidence of articular lesions, while in females this correlation was lacking.

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