Reactions of androsta-3,5-dienes with m-chloroperbenzoic acid
- 1 January 1980
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Perkin Transactions 1
- No. 11,p. 2581-2586
- https://doi.org/10.1039/p19800002581
Abstract
The reaction of androsta-3,5-diene and of androsta-3,5-dien-17-one with one or 2 molar equiv. of m-chloroperbenzoic acid give complex mixtures of products. Only low yields of diepoxides are formed using 2 equiv. of peracid in ether as solvent, unsaturated vic-3,4-diols being the major products. Use of 1 equiv. of peracid leads, inter alia, to unsaturated hydroxy-m-chlorobenzoates. The formation of these and other products are discussed.This publication has 2 references indexed in Scilit:
- NMR Studies on steroids—VIITetrahedron, 1965
- Isolation of Δ3:5-androstadiene-17-one from the urine of a man with a malignant tumour of the adrenal cortexBiochemical Journal, 1937