Radioimmunoassayable Serum Somatomedin B in Normal Subjects and in Patients with Acromegaly and Pituitary Dwarfism: Effects of Human Growth Hormone Therapy
- 1 October 1980
- journal article
- research article
- Published by Georg Thieme Verlag KG in Hormone and Metabolic Research
- Vol. 12 (10) , 516-519
- https://doi.org/10.1055/s-2007-999189
Abstract
The results obtained with a radioimmunoassay for serum somatomedin B (SmB) in 29 normal subjects, in 33 pituitary dwarfs (GHD) and 6 acromegalic patients are reported. There were no significant differences between the basal SmB levels of the GHD and the normal subjects while a higher value was observed in the acromegalic group (P < 0.01). After acute human growth hormone [hGH] administration a parallel increase of SmB serum levels and plasma growth hormone was seen (r = 0.562; P < 0.01). Of 12 GHD subjects SmB serum levels increased only in 5, after chronic hGH administration.This publication has 0 references indexed in Scilit: