Production by Semicarbazide of Gross Skeletal Changes in Rats Similar to Osteolathryism.
- 1 January 1958
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 97 (1) , 112-114
- https://doi.org/10.3181/00379727-97-23661
Abstract
Semicarbazide hydrochloride, when incorporated into Rockland rat stock diet and fed to weanling rats at levels of 0.05-0.25%, produced gross skeletal changes very similar to those produced by sweetpeas or [beta]-aminopropionitrile (BAPN). Damage to the aortic media also occurred, but developed more slowly and was less severe than when BAPN is fed. Dissecting aneurysms were not observed.Keywords
This publication has 10 references indexed in Scilit:
- Experimental Lathyrism in Mice Fed Diets Containing Sweet Peas or -aminopropionitrile.Experimental Biology and Medicine, 1957
- Production of Beak and Skeletal Malformations of Chick Embryo by SemicarbazideExperimental Biology and Medicine, 1956
- The Toxic Component of the Singletary Pea (Lathyrus pusillus)Journal of the American Pharmaceutical Association (Scientific ed.), 1956
- Teratogenic Effects of Lathyrus odoratus Seeds on Development and Regeneration of Vertebrate Limbs.Experimental Biology and Medicine, 1955
- Lathyrus Factor Activity of Beta-Aminopropionitrile and Related Compounds.Experimental Biology and Medicine, 1955
- Isolation, Structure and Synthesis of a Lathyrus Factor From L. Odoratus1,2Journal of the American Chemical Society, 1955
- Production of Experimental Lathyrism in the Rat by Two Different Beta-substituted EthylaminesExperimental Biology and Medicine, 1955
- EFFECT OF SWEET PEA MEAL ON THE RAT AORTA1955
- LESIONS OF THE SKELETON AND OF OTHER MESODERMAL TISSUES IN RATS FED SWEET-PEA (LATHYRUS ODORATUS) SEEDSJournal of Bone and Joint Surgery, 1954
- Lathyrism in the RatJournal of Nutrition, 1933