Use of M1–M5 Muscarinic Receptor Knockout Mice as Novel Tools to Delineate the Physiological Roles of the Muscarinic Cholinergic System
- 1 January 2003
- journal article
- review article
- Published by Springer Nature in Neurochemical Research
- Vol. 28 (3/4) , 437-442
- https://doi.org/10.1023/a:1022844517200
Abstract
In this review we report recent findings on the physiological role of the five known muscarinic acetylcholine receptors (mAChRs) as shown by gene targeting technology. Using knockout mice for each...Keywords
This publication has 37 references indexed in Scilit:
- Role of specific muscarinic receptor subtypes in cholinergic parasympathomimetic responses, in vivo phosphoinositide hydrolysis, and pilocarpine‐induced seizure activityEuropean Journal of Neuroscience, 2003
- Characterization of Central Inhibitory Muscarinic Autoreceptors by the Use of Muscarinic Acetylcholine Receptor Knock-Out MiceJournal of Neuroscience, 2002
- Muscarinic Agonist-Mediated Increases in Serum Corticosterone Levels Are Abolished in M2 Muscarinic Acetylcholine Receptor Knockout MiceThe Journal of Pharmacology and Experimental Therapeutics, 2002
- Hyperactivity, elevated dopaminergic transmission, and response to amphetamine in M1 muscarinic acetylcholine receptor-deficient miceProceedings of the National Academy of Sciences, 2001
- M1 Muscarinic Acetylcholine Receptors Activate Extracellular Signal-Regulated Kinase in CA1 Pyramidal Neurons in Mouse Hippocampal SlicesMolecular and Cellular Neuroscience, 2001
- Muscarinic receptor ligands and their therapeutic potentialCurrent Opinion in Chemical Biology, 1999
- International Union of Pharmacology. XVII. Classification of Muscarinic Acetylcholine ReceptorsPharmacological Reviews, 1998
- Muscarinic acetylcholine receptor subtypes in the human irisBrain Research, 1998
- Expression of muscarinic acetylcholine and dopamine receptor mRNAs in rat basal ganglia.Proceedings of the National Academy of Sciences, 1990
- AN UNUSUAL TYPE OF SYMPATHETIC GANGLIONIC STIMULANT1961