Morphometric assessment of ovarian stromal proliferation–a clinicopathological study

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Abstract
Ovarian stromal hyperplasia is commonly observed in peri‐ and post‐menopausal ovaries. Assessment has, hitherto, been largely subjective or dependent on arbitrary criteria, which has made comparison of studies difficult. In this study, the stroma of a large number of ovaries was assessed morphometrically. Data were related to clinicopathological and cytomorphological information. A significant association was noted between the degree of stromal proliferation and post‐menopausal endometrial adenocarcinoma (P=0.004). There were no significant correlations between the degree of stromal proliferation and average cytomorphological dimensions.