Immunoglobulin A Production in Ataxia Telangiectasia
- 26 November 1965
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 150 (3700) , 1175-1177
- https://doi.org/10.1126/science.150.3700.1175
Abstract
Serum from five patients with ataxia telangiectasia contained no detectable immunoglobulin A (IgA). However, there was evidence (by immunofluorescence) of IgA in the bone marrow of the three patients so examined, suggesting that the defect in IgA production was not complete. IgA was in the saliva of all five patients and in the parotid gland of the one patient studied. This is further evidence of IgA synthesis by the salivary glands.This publication has 5 references indexed in Scilit:
- Quantitative Determination of Serum Immunoglobulins in Antibody-Agar PlatesThe Journal of Immunology, 1965
- CHARACTERISTICS OF AN IMMUNE SYSTEM COMMON TO CERTAIN EXTERNAL SECRETIONSThe Journal of Experimental Medicine, 1965
- Nomenclature for human immunoglobulinsImmunochemistry, 1964
- ATAXIA TELANGIECTASIA A DYSGAMMAGLOBULINÆMIA WITH DEFICIENT γ1A (β2A)-GLOBULINThe Lancet, 1964
- Immunohistologic Localization of Gamma-1-Macroglobulins, Beta-2A-Myeloma Proteins, 6.6 S Gamma-Myeloma Proteins and Bence Jones ProteinsBlood, 1963