Long-term cultivation of Plasmodium falciparum in media with commercial non-serum supplements
- 1 August 1997
- journal article
- Published by Springer Nature in Zeitschrift Fur Parasitenkunde-Parasitology Research
- Vol. 83 (7) , 734-736
- https://doi.org/10.1007/s004360050330
Abstract
Continuous cultivation of both drug-sensitive and drug-resistant strains of Plasmodiumfalciparum was achieved using a mixture of commercially available serum substitutes. This provides easier standardisation of experimental data and minimises the risk of infection from handling of human serum. In addition, Nutridoma SR and AlbuMAXI are readily available and are biologically defined. Parasites grown in serum-free medium are morphologically and metabolically identical to those cultivated in medium supplemented with 10% human serum.Keywords
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