A Convenient Synthesis of Enantiomerically Pure (2R,3S)- and (2S,3R)-3-Hydroxy-2-methylbutanoic Esters
- 1 January 1988
- journal article
- research article
- Published by Georg Thieme Verlag KG in Synthesis
- Vol. 1988 (07) , 538-540
- https://doi.org/10.1055/s-1988-27629
Abstract
Both enantiomers of erythro methyl or ethyl 3-hydroxy-2-methylbutanoate were prepared by reaction of lithium dimethylcuprate with enantiomerically pure cis-2,3-epoxybutanoic esters derived from L- or D- threonine.Keywords
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