Evaluation of an antigen-capture enzyme immunoassay for rapid diagnosis ofMycoplasma pneumoniae infection
- 1 November 1993
- journal article
- research article
- Published by Springer Nature in European Journal of Clinical Microbiology & Infectious Diseases
- Vol. 12 (11) , 872-875
- https://doi.org/10.1007/bf02000413
Abstract
A new enzyme immunoassay (EIA; Enzygost) for rapid detection ofMycoplasma pneumoniae antigen was evaluated in 51 young adults with acute respiratory infection. The EIA results using sputa and nasopharyngeal aspirates were compared with those of serological antibody tests, culture and a DNA probe. In sputum the sensitivity of the EIA ranged from 40 % to 81 % and the specificity from 64 % to 100 %, depending on the reference method. In nasopharyngeal aspirates the sensitivity was well below 20 %, but the test was nearly 100 % specific.Keywords
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