Release of Peripherally Stored Insulin During Acute Muscular Work in Man

Abstract
Exercise enhanced the uptake of glucose and FFA in healthy men. The arteriovenous insulin gradients were positive at rest and in the recovery period. During and after exercise the arteriovenous insulin differences reversed, regardless whether the insulin concentrations were elevated or not. The reversal of the arteriovenous insulin differences during and after exercise is consistent with a release of insulin from peripheral stores. The mechanism of exercise enhanced uptake of both glucose and FFA are discussed. 1 Supported by the Deutsche Forschungsgemeinschaft.

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