Amino acid sequence of the oligomycin sensitivity‐conferring protein (OSCP) of beef‐heart mitochondria and its homology with the δ‐subunit of the F1‐ATPase of Escherichia coli
- 23 January 1984
- journal article
- research article
- Published by Wiley in FEBS Letters
- Vol. 166 (1) , 19-22
- https://doi.org/10.1016/0014-5793(84)80036-8
Abstract
The complete amino acid sequence of the oligomycin sensitivity‐conferring protein (OSCP) of beef‐heart mitochondria is reported. The protein contains 190 amino acids and has a molecular mass of 20 967. Its structure is characterized by a concentration of charged amino acids in the two terminal segments (N 1–77 and C 128–190) of the protein, whereas its central region is more hydrophobic. The earlier reported homology of the protein with the δ‐subunit of E. coli F1, based on the terminal amino acid sequences of OSCP, is further substantiated.Keywords
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