Heat stress in the presence of low RNA polymerase activity increases chromosome copy number in Escherichia coli
- 1 May 1988
- journal article
- research article
- Published by Springer Nature in Molecular Genetics and Genomics
- Vol. 212 (2) , 203-206
- https://doi.org/10.1007/bf00334685
Abstract
A temperature shift-up accompanied by a reduction in RNA polymerase activity in Escherichia coli causes an increased rate of initiation leading to a 1.7- to 2.2-fold increase in chromosome copy number. A temperature shift-up without a reduction in polymerase activity induces only a transient non-scheduled initiation of chromosome replication caused by heat shock with no detectable effect on chromosome copy number.This publication has 23 references indexed in Scilit:
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